Fantasy football news and injury updates

Ranking assumes full PPR, one QB, no IDP. Set your league

Signal 15 most important first

• Out ESPN NFL Injury Report SF Isaac GuerendoRB 2d
  Isaac Guerendo: Out

  Aug 30: Guerendo (pectoral) was placed on the reserve/PUP list Sunday, Jeremy Fowler of ESPN reports.

  Why it's #1 Out

• Out ESPN NFL Injury Report SF Isaac GuerendoRB Oct 25
  Isaac Guerendo: Out

  Aug 30: Guerendo (pectoral) was placed on the reserve/PUP list Sunday, Jeremy Fowler of ESPN reports.

  Why it's #2 Out

• Out ESPN NFL Injury Report SF Isaac GuerendoRB Oct 18
  Isaac Guerendo: Out

  Aug 30: Guerendo (pectoral) was placed on the reserve/PUP list Sunday, Jeremy Fowler of ESPN reports.

  Why it's #3 Out

• Out ESPN NFL Injury Report SF Isaac GuerendoRB Oct 11
  Isaac Guerendo: Out

  Aug 30: Guerendo (pectoral) was placed on the reserve/PUP list Sunday, Jeremy Fowler of ESPN reports.

• Out ESPN NFL Injury Report SF Isaac GuerendoRB Oct 4
  Isaac Guerendo: Out

  Aug 30: Guerendo (pectoral) was placed on the reserve/PUP list Sunday, Jeremy Fowler of ESPN reports.

• Out ESPN NFL Injury Report SF Isaac GuerendoRB Sep 28
  Isaac Guerendo: Out

  Aug 30: Guerendo (pectoral) was placed on the reserve/PUP list Sunday, Jeremy Fowler of ESPN reports.

• INJ Matt Maiocco (X) SF Christian KirkWR De'Zhaun StriblingWR Isaac GuerendoRB Jake TongesTE Mykel WilliamsDL Nate HobbsDB Nick MartinLB Sam OkuayinonuDL +5 more Sep 16 upd
  49ers expected back from injury lists this season: DL Mykel Williams WR Christian Kirk CB Nate Hobbs LB Nick Martin OL Austen Pleasants RB Isaac Guerendo ??? DL Sam Okuayinonu WR De’Zhaun Stribling TE Jake Tonges
  1 more updatefrom 1 source

  • Sep 16 Matt Maiocco (Bluesky) 49ers expected back from injury lists this season: DL Mykel Williams WR Christian Kirk CB Nate Hobbs LB Nick Martin OL Austen Pleasants RB Isaac Guerendo ??? DL Sam Okuayinonu WR De’Zhaun Stribling TE Jake Tonges+1
• Out ESPN NFL Injury Report SF Isaac GuerendoRB Sep 24
  Isaac Guerendo: Out

  Aug 30: Guerendo (pectoral) was placed on the reserve/PUP list Sunday, Jeremy Fowler of ESPN reports.

• Out ESPN NFL Injury Report SF Isaac GuerendoRB Sep 20
  Isaac Guerendo: Out

  Aug 30: Guerendo (pectoral) was placed on the reserve/PUP list Sunday, Jeremy Fowler of ESPN reports.

• Out ESPN NFL Injury Report SF Isaac GuerendoRB Sep 13
  Isaac Guerendo: Out

  Aug 30: Guerendo (pectoral) was placed on the reserve/PUP list Sunday, Jeremy Fowler of ESPN reports.

• Out ESPN NFL Injury Report SF Isaac GuerendoRB Aug 30 upd
  Isaac Guerendo: Out

  Aug 30: Guerendo (pectoral) was placed on the reserve/PUP list, Jeremy Fowler of ESPN reports.

  4 more updatesfrom 3 sources

  • Aug 30 ESPN NFL Injury Report Isaac Guerendo: Out
  • Aug 30 Matt Maiocco (X) RB Isaac Guerendo and DL Mykel Williams begin the season on reserve/PUP. They are eligible to return to action after four games.+1
  • Aug 30 NFL Daily News (Bluesky) Fowler: Isaac Guerendo (pec) placed on reserve/PUP; will miss at least 4 games.
  • Aug 30 Jeremy Fowler (X) 49ers are moving running back Isaac Guerendo (pec) to reserve/PUP, per source, ruling him out for the first four games of the season.
• Out ESPN NFL Injury Report SF Isaac GuerendoRB Sep 6
  Isaac Guerendo: Out

  Aug 30: Guerendo (pectoral) was placed on the reserve/PUP list Sunday, Jeremy Fowler of ESPN reports.

• INJ David Lombardi (X) SF Demarcus RobinsonWR Isaac GuerendoRB James Thompson Jr.DL Mykel WilliamsDL Sep 21
  Here are the 49ers eligible to return from IR. 6 of them can realistically come back and Mykel Williams and Isaac Guerendo can return from PUP — fortunately for SF, only NFI counts toward the 8, not PUP. But this is factoring into Demarcus Robinson/James Thompson Jr. IR thinking
• Out ESPN NFL Injury Report SF Isaac GuerendoRB Sep 1
  Isaac Guerendo: Out

  Aug 30: Guerendo (pectoral) was placed on the reserve/PUP list Sunday, Jeremy Fowler of ESPN reports.

• INJ David Lombardi (X) SEA SF Isaac GuerendoRB Mykel WilliamsDL Sep 21
  New NFL rule allows for returns from PUP to start practicing this coming week — Week 3. Means that Mykel Williams and Isaac Guerendo can be back out at practice Wednesday if ready for the 49ers. Week 5 (at Seattle) would be their first game eligibility

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